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85 In a randomized controlled trial, 80 people between ages 35 and 55 years with self-assessed sleep problems took 1 gram of a branded form of magnesium-L-threonate called Magtein, providing 72 mg of elemental magnesium, or a placebo daily for 21 days

Senolytic FOXO4-DRI can inhibit FOXO4 binding by disrupting the p53-FOXO4 interaction and selectively cause apoptosis via p53 nuclear exclusion in senescent cells and aging mouse models, which may be a promising approach for preventing senescence 11

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